During a period of creative and emotional crisis in 2022, Apostolides stumbled on a scientific article that would profoundly change her understanding of the human mind. Ten months later, she was interviewing the article's lead author and embarking on a journey to unravel current approaches to mental health. Go/No-Go documents her quest to decipher research underlying new treatments for mental disorders-- and to understand how it is reshaping our fundamental sense of ourselves. She talks with leading neuroscientists, gathering info about studies, methods, and the resulting treatments that are in the pipeline, soon to be offered to people. All the while, she reflects on her own experiences, making the science more understandable and relevant. With writing that's propulsive yet tethered to hard data, she prompts us to look at how contemporary neuroscience is redefining who we are and why we struggle. Through vital questions, readers come to see the flaws and failures of the current approach to mental health-- while also learning how society can change course to better support people in their own journey. Go/No-Go is a groundbreaking addition to an urgent dialogue about mental health.