This book selects the most important scientific papers related to kidney disease and comments on their significance within the wider field. Fascinating reading for both nephrologists and medical historians, no doubt giving rise to further debate over the origins and progress of nephrology. What is the niche for this book and who should buy it? First and foremost, it has to be said that it is truly unique. It will be quite useful for seasoned nephrologists and trainees alike, especially if they want to take a closer look at the origins of our current clinical practice. Young researchers may find it thought provoking as well in that one can learn how seminal discoveries and renal research evolved throughout the centuries ... what it does well is give a fascinating insight into the history of our specialty and presents many of the groundbreaking papers that shaped this history.